RESUMO
In the present study, we report the preparation of antifungal and non-cytotoxic polymer nanocomposites with potential application in biomedical materials. Dodecanethiol-protected silver nanoparticles (AgNPs-DDT) were synthesized by a reduction/precipitation method and dispersed in chloroform to obtain stable colloidal dispersions. PBAT-based nanocomposites containing 0.25, 0.5 and 2â¯wt% AgNPs-DDT were prepared by casting method. The incorporation of AgNPs-DDT in PBAT matrix resulted in nanocomposites which combine improved mechanical performance and antifungal properties with a non-cytotoxic characteristic.
Assuntos
Antifúngicos/farmacologia , Nanopartículas Metálicas/química , Nanocompostos/química , Poliésteres/química , Prata/química , Compostos de Sulfidrila/química , Varredura Diferencial de Calorimetria , Candida albicans/efeitos dos fármacos , Morte Celular/efeitos dos fármacos , Linhagem Celular , Elasticidade , Humanos , Testes de Sensibilidade Microbiana , Nanocompostos/ultraestrutura , Tamanho da Partícula , Reologia , ViscosidadeRESUMO
Nanocomposites of recycled poly(ethylene terephthalate) (rPET) containing 2.5 wt% and 5.0 wt% of montmorillonite modified with organophilic quaternary ammonium salt (DELLITE 67G) were prepared by melt compounding using a co-rotating twin-screw type extruder with two organoclay contents were used: 2.5 wt% and 5.0 wt% and were prepared using two different rotation speeds: 150 and 250 rpm. Thermal characterization (analysis) of the nanocomposites was performed using differential scanning calorimetry (DSC) analysis. The results from DSC measurements showed that the addition of organoclay affects recycled PET's crystallization for two screw rotation speeds studies. The nucleating effect of organoclay was investigated. Morphological analysis using Transmission Electron Microscopy (TEM) revealed the presence of fully exfoliated clay platelets in samples prepared at 150 rpm.
